From complex sample to pure answer.
HIPSOUL is an integrated analytical & purification solutions provider. One laboratory partner for HPLC/UHPLC analysis, method development, impurity identification, preparative purification, reference standards — and the columns and consumables to run them.
Every difficult sample has a bottleneck. Pick yours.
Select the challenge closest to your project — we’ll point you to the HIPSOUL capability that removes it.
ONE PARTNER
Stop coordinating four vendors. Brief one team.
Analysis, method development, purification, standard preparation and consumables usually live with different suppliers — each hand-off costing time, context and sample. At HIPSOUL they share one lab, one project owner and one report chain.
- Continuity of sample knowledge. The chemist who analyzed your sample plans its purification.
- Methods that transfer. Analytical methods are developed on the same phases we supply as columns.
- One commercial relationship. Single quote, single NDA, single point of accountability.
Answers you can put in a report — or a filing.
HPLC/UHPLC and LC-MS based analytical work, delivered with full chromatograms, raw data and documented conditions. Hover any card for scope.
Method Development
Robust, transferable HPLC/UHPLC methods built for your matrix and your instruments.
- Phase & gradient screening
- Forced degradation fit
- Validation-ready SOP
Impurity Identification
Isolation and structural characterization of unknown and related substances.
- LC-MS profiling
- Impurity enrichment
- ICH Q3A/Q3B context
Sample Testing
Assay, purity, content uniformity and related-substance testing for routine and project work.
- Per-batch or campaign
- Client or pharmacopoeial methods
- Fast COA-style reporting
HPLC / UHPLC Analysis
High-resolution separations on modern instruments with a deep column library.
- RP, NP, HILIC, chiral
- Sub-2 µm UHPLC
- Full audit-trail data
From crude mixture to single peak.
Preparative chromatography from milligram screening to multi-gram delivery — for natural products, drug impurities and difficult synthetic mixtures.
Natural Product Purification
Target isolation from plant extracts, fermentation broths and complex biological matrices.
- Extract pre-fractionation
- Orthogonal polishing
- Structure confirmation
Drug Impurity Purification
Enrichment and isolation of trace impurities at the quantities your tox and ID work needs.
- From <0.1% area peaks
- mg-level recovery
- Purity COA included
Preparative Chromatography
Analytical-to-prep scale-up with documented loading studies and recovery data.
- Up to multi-gram scale
- Focused fraction collection
- Solvent-exchange & drying
Compound Isolation
Recovery of single components from reaction mixtures, degradation studies and process streams.
- Unknowns welcome
- Stability-aware handling
- Identity package on request
Drag to purify
CRUDE EXTRACT → ISOLATED TARGET | Purity: 41.2%Reference materials, prepared to order.
When the standard you need doesn’t exist in a catalog, we isolate, purify and characterize it for you.
Reference Standard Preparation
Working and secondary reference standards with assigned purity and full characterization data.
- HPLC purity assignment
- MS / NMR identity data
- Stability guidance
Control Sample Preparation
QC control and system-suitability samples matched to your method and matrix.
- Batch-to-batch consistency
- Custom concentrations
- Documented preparation
Custom Compound Preparation
Milligram-to-gram quantities of impurities, metabolite analogs and rare natural products.
- Isolation or semi-synthesis route
- Purity to specification
- COA with every shipment
The hardware behind every clean baseline.
Columns and flow-path consumables manufactured to tight QC — the same parts our own laboratory runs every day.
HPLC & UHPLC Columns
C18/C8, HILIC, phenyl and specialty phases; 1.8–10 µm; analytical to prep dimensions.
Request column list →Guard Columns
Analytical and preparative guard cartridges and holders that extend main-column lifetime.
Analytical & prep →Inline Filters
Pre-column inline filters, 0.5–2 µm frits, protecting UHPLC systems from particulates.
0.5 / 1 / 2 µm →Stainless Steel Tubing
Pre-cut and coiled 316 SS HPLC tubing in standard IDs, deburred and passivated.
Custom lengths →Solvent Inlet Filters
Mobile-phase inlet filters in SS and PEEK, 2–20 µm, for clean solvent delivery.
SS & PEEK →Empty Columns
Empty column hardware for self-packing — tubes, frits and end fittings, analytical to prep.
Self-pack hardware →Fittings & Connectors
Ferrules, unions, nuts and adapters in SS and PEEK for leak-free flow paths.
Full catalog →OEM & Custom Programs
Private-label packing, custom dimensions and recurring-supply agreements for labs and distributors.
Talk to sales →Real instruments. Real throughput. Real data.
Your project runs on a working analytical and preparative laboratory — not a brokered network.
Inside the laboratory
DRAG TO EXPLORE
LAB PHOTO · SAMPLE PREP
LAB PHOTO · HPLC SYSTEM
LAB PHOTO · WET LAB
LAB PHOTO · DATA REVIEW
LAB PHOTO · SPECTRUM QC
LAB PHOTO · COA REPORT
HPLC
Quaternary and binary systems with UV/DAD detection for routine and project analysis.
UHPLC
Sub-2 µm separations at high pressure for speed, resolution and low solvent burn.
Preparative HPLC
Semi-prep to prep-scale systems with high-flow pumps and large-ID column hardware.
LC-MS
Mass-directed identification of unknowns, impurities and co-eluting components.
Fraction Collection
Time-, threshold- and mass-triggered collection for clean cuts on every prep run.
Sample Preparation
Extraction, filtration, SPE and dilution workflows matched to your matrix.
Method Validation
Specificity, linearity, accuracy, precision and robustness studies to ICH Q2.
Solvent Recovery & Drying
Rotary evaporation and lyophilization to deliver purified compounds shipment-ready.
Data & Reporting
Audit-trailed CDS data, full chromatograms and bilingual (EN/中文) project reports.
Built for laboratories that answer to auditors.
Five steps from sample to deliverable.
Sample Submission
Ship under NDA with our simple submission form; we confirm receipt and condition same day.
Technical Evaluation
A chemist screens your sample and returns a written approach, timeline and fixed quote.
Method Development
Phase and condition screening until separation, recovery and robustness meet target.
Analysis / Purification
Production runs with in-process checks; you receive progress updates, not silence.
Report & Delivery
Full report, raw data and — for purification — your compound with purity COA.
What this looks like in practice.
Representative projects — details anonymized under NDA. Ask for the application note closest to your problem.
Co-eluting impurity resolved and identified before a regulatory deadline
A 0.18% shoulder peak in an API related-substances method was baseline-resolved on an alternative phase, enriched by prep-HPLC and identified by LC-MS — with enough material recovered for the client’s reference file.
Multi-gram isolation of a bioactive compound from plant extract
A two-stage preparative strategy — reversed-phase capture followed by orthogonal polishing — took a 23%-pure enriched extract to a single-peak product, delivered dried with full chromatographic data.
A 38-minute legacy method rebuilt as a 9-minute UHPLC method
Phase re-screening and gradient redesign cut run time by 76% while improving resolution of the critical pair — validated for specificity and precision, then transferred with a written protocol.
Milligram screen to multi-gram campaign without changing selectivity
Loading studies on analytical hardware predicted prep behavior on the same phase chemistry; the campaign scaled 400× with no re-development and consistent fraction purity across batches.
Six reasons technical buyers choose us.
Analysis + purification, integrated
The team that characterizes your sample designs and runs its purification — no translation loss between vendors.
Real laboratory capability
Work happens on our own HPLC, UHPLC, prep-LC and LC-MS instruments, with capacity we control.
Custom by default
Every project gets its own approach document. We don’t force your sample into a standard package.
Fast, committed response
Technical reply within 48 hours, written timelines, and proactive updates while your project runs.
Engineer-level support
Your contact is a chromatographer, not a ticket queue — in English or Chinese, your choice.
Consumables + services together
Methods we develop run on columns we supply, so what works in our lab keeps working in yours.
Learn before you brief us.
Application Notes
Worked separations: conditions, chromatograms and results for common problem classes.
Browse notes →Method Guides
Practical guidance on phase selection, gradient design and troubleshooting.
Read guides →Product Downloads
Column datasheets, care instructions and consumable compatibility charts.
Download PDFs →FAQ
Direct answers to the questions every new B2B client asks before submitting.
Jump to FAQ ↓Before you submit a sample
What sample types can you handle?
Small-molecule APIs and intermediates, plant and natural-product extracts, fermentation products, food and chemical matrices, and synthetic reaction mixtures. If you’re unsure, describe the sample in your inquiry — evaluation is free and confidential.
Can you develop custom HPLC methods?
Yes — method development is a core service. We screen phases and conditions against your acceptance criteria, document the final method as a transferable SOP, and can support validation to ICH Q2 if required.
Can you purify unknown compounds?
Yes. We routinely isolate unidentified peaks and unknown components, using LC-MS to track the target through purification. Structural characterization data can be included in the deliverable.
Can you provide preparative chromatography?
Yes — from semi-prep isolation of milligram quantities to multi-gram campaigns, with loading studies, fraction analysis, solvent exchange and drying handled in-house.
Do you supply columns and consumables?
Yes. HIPSOUL manufactures and supplies HPLC/UHPLC columns, guard columns, inline filters, tubing, solvent inlet filters, empty column hardware and fittings — including OEM and custom-dimension programs.
How do I submit samples?
Start with the inquiry form below or email our technical team. We’ll sign an NDA if needed, send a submission form and shipping instructions, and confirm receipt and sample condition the day your package arrives.
Have a complex sample, a difficult impurity, or a purification challenge?
Send a short description. A HIPSOUL chromatographer — not a sales bot — replies with a technical approach within 48 hours.
NDA available · EN / 中文 · Free technical evaluation